2012 ATS Abstracts

Abstracts Submitted by COPDGene Investigators for the
2012 Annual Meeting of the American Thoracic Society

1. Trachea Air: Internal Reference Standard for CT Lung Densitometry.  Philip Judy.
2. Common Genetic Risk Variants Correlate with Hypoxemia in COPD Cases in a Multi-Stage Genome-wide Association Study.  Merry-Lynn McDonald.
3. Pulmonary Vascular Remodeling Quantification in Inspiratory Volumetric CT Using Scale-Space Particles. Raul San Jose Estepar.
4. Diabetes is Not Associated with Reduced Pulmonary Function in COPD. Greg Kinney.
5. Correlation of Emphysema Measured by Multidetector Computed Tomography with Spirometry: Lobar Contribution. Surya Bhatt.
6. Chronic Bronchitis Predicts Greater Frequency and Severity of COPD Exacerbations in Moderate to Severe COPD.  Victor Kim.
7. Prediction of Future COPD Respiratory Exacerbations in Smokers.  The COPDGene Cohort.  Russ Bowler.
8. Non-Obstructive Chronic Bronchitis in the COPDGene Cohort.  Meilan Han
9. Asymptomatic COPD in the COPDGene Cohort.  Meilan Han.
10. COPD Comorbidities and Its Impact on Health Status and Quality of Life.  A COPDGene Substudy.  Meilan Han.
11. Genome-Wide Association Study for Local Histogram Emphysema Patterns Identifies Loci Near CHRNA3/5 and MMP12/MMP3.  Peter Castaldi.
12. Novel Genetic Determinants of Lung Functions from Large Population-Based Studies and Association with COPD: Validation and eQTL Analysis.  Peter Castaldi.
13. Reproducibility of Visual Scoring of COPD Phenotypes.  Doug Stinson.
14. Clinical Predictors of Thromboembolic Events in Patients with Chronic Obstructive Pulmonary Disease.  Nishant Goel.
15. Gender Differences in Bone Mineral Density in Subjects with COPD: Males at Increased Risk of Bone Loss.  Joshua Jaramillo.
16. Classification Tree Approach to Defining Exacerbation Subgroups in COPDGene. Meilan Han.
17. A Genome-Wide Association Study of Bronchodilator Responsiveness in Four Cohorts with COPD.  Megan Hardin.
18. Hyperinflated and Gas Trapped COPD Patients with Emphysema Predominant Phenotype Have Worse Lung Function, Exercise Performance, Quality of Life, and BODE Score. Nathaniel Marchetti.
19. Paired Inspiratory and Expiratory Chest CT Scans to Assess for Small Airway Disease in the COPDGene Study.  Craig Hersh.
20. Prevalence and Predictors of CT Findings Concerning for Malignancy in a Population of Smokers at Risk for Lung Cancer.  Jamie Garfield.
21. Impact of Differing Convolution Kernels on Quantitative CT Measures of Lung Density and Correlation with Physiology in Smokers: B31f vs. B35f.   Jordan Zach.
22. Factors Associated with Exacerbations in Individuals with GOLD Stage II COPD.  Brendan Carolan.
23. The Association of Plasma Biomarkers with Phenotypic Parameters in COPD.  Brendan Carolan.
24. Emphysema Types Quantification by Local Density Histogram in CT.  Raul San Jose Estepar.
25. Exome Sequencing in Severe COPD Cases and Resistant Smoking Controls from COPDGene.  Michael Cho.
26. Interstitial Lung Abnormalities and Reduced Exercise Capacity.  Tracy Wanner.
27. Clinical Impact of CT Radiological Feature of Bronchiectasis in the COPDGene Cohort.  Jeff Stewart.
28. Exome Sequencing Identifies Rare Functional Coding Variants in HK2, MTRR, and DCAF5 that Determine Lung Function Decline in COPD.  Rasika A. Mathias.
29. Overlap Syndrome Is Associated with Cardiovascular Disease.  Jennifer L. Black-Shinn.
30. Clinical Characteristics of COPD Patients According to the Pattern of Emphysema on High Resolution CT.  Jeff Stewart.